Workshop Details
Phase Separation in Biology and Disease
03/04/2024 - 03/08/2024
Meeting Description:

Phase separation (PS) has emerged in the last 15 years as a ubiquitous mechanism for organizing biomolecules within condensed, often liquid-like, bodies in cells to perform a dizzying array of biological processes. For example, phase separation is known to mediate nucleolar organization, super enhancer-dependent gene expression, gene silencing, ribosome biogenesis, cell fate determination in early development, activity-dependent protein translation in neurons, endocytosis, T cell receptor signaling, and many other processes too numerous to mention. Further, aberrant phase separation caused by gene mutations, or through altered protein regulation, is associated with myriad human diseases, including neurodegenerative disorders, many different human cancers, and other human disorders.

This workshop will focus on several cutting-edge topics, including:
- Relationships between biomolecular phase separation and biological function, both within the cytoplasm and the nucleus;

- Links between genetic and epigenetic mechanisms of altered cellular regulation, aberrant phase separation and disease etiology;

- Strategies to therapeutically modulate disease mechanisms by targeting aberrant biomolecular condensates.

Workshop format:
Telluride Science workshops are very small meetings (<25 attendees) which feature in depth discussion of topics at the interfaces of physics, chemistry, data science and biology. All attendees will present a ~30 minute lecture and are encouraged to stay for the entire time. Meetings will be held in the mornings, allowing for afternoon discussions and outdoor activities, including skiing, snowshoeing, snowmobile driving, sledding, walking, visiting coffee houses, etc. Discussions continue over ad hoc large and small group dinners.

Diversity, Equity & Inclusion:
We strive for diversity, equity and inclusion amongst attendees, including participants spanning diverse genders, races, religious preferences, and gender identities, as well as those spanning diverse career-stages. In addition to attracting academic scientists, an important goal is to engage scientists from biotech companies focused on "drugging biomolecular condensates" that have emerged [e.g., Dewpoint Therapeutics ( and Nereid Therapeutics (].



We wish to ensure an intimate workshop setting, with ~25 participants. If you are interested in attending, but have not received an invitation, please contact the workshop organizer before registering.

Telluride Science is about expanding the frontiers of science, exploring new ideas, and building collaborations. The workshop schedule will allow for substantial unstructured time for participants to talk and think. All participants are expected to stay for the entire duration of the workshop. Scientists are encouraged to consider bringing family or friends. There is information on childcare and family activities at Please contact Cindy Fusting at with any questions or for assistance in coordinating care.

Meeting Venue:

Ah Haa School for the Arts
155 W Pacific Ave Telluride, CO 81435
Click Here for Directions

Meeting Details:

Workshop Price: $ 449.00
Early Bird Lodging Discount Available Until: 11/15/2023

A $100.00 discount is applied to your lodging cost when you register before 11/15/2023.

Cancellation Policy: Once a credit card has been charged, cancelled registrations will be subject to a cancellation fee. Registration fees will be automatically processed once registration is complete. A $25 cancellation fee will be retained from a registration refund. Lodging fee payments will be processed 60 days prior to arrival, and a $100 cancellation fee will apply if cancellations occur after a lodging fee payment is completed. Telluride Science can only guarantee a refund for the remaining lodging fees if requested prior to the cancellation deadline that is specific to each lodging provider. Telluride Science recommends that participants purchase travel insurance to protect against unforeseen, last-minute travel plan changes.

Phase Separation in Biology and Disease Registered Meeting Participants:
Participant Organization
Boeynaems, Steven Baylor College of Medicine
Bugaj, Lukasz University of Pennsylvania
Calo, Eliezer MIT
Eftekharzadeh, Bahareh Nereid Therapeutics
Elbaum, Shana ASRC, CUNY
Holt, Liam New York University
Kriwacki, Richard St. Jude Children's Research Hospital
Lee, Yohan University of Texas at Austin
Milovanovic, Dragomir German Center for Neurodegenerative Diseases (DZNE)
Mitrea, Diana Dewpoint Therapeutics
Mueller-Cajar, Oliver Nanyang Technological University
Reinkemeier, Christopher Dieter ETH Zürich
Sabari, Benjamin UT Southwestern
Sanulli, Serena Stanford University
Strader, Lucia Duke University
Wadsworth, Gable University at Buffalo, SUNY
Zhang, Huaiying Carnegie Mellon University
Zweckstetter, Markus German Center for Neurodegenerative Diseases

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