While an overwhelming majority of biophysical studies on proteins are performed on dilute solutions, there is now a rapidly growing appreciation of the potential effects of intermolecular excluded volume ("crowding") within the highly volume-occupied cellular interior. A semiquantitative picture of crowding effects in vitro, based on simplified models, has been developed. The next steps toward an understanding of crowding effects within cellular environments are challenging but important for proper modeling of protein functions in vivo. This workshop is organized to address these next steps. Among the topics will be the latest results on the microstructures of the various components of the cytoplasm and on the compositions of the various organelles; the in silico modeling and in vitro mimicking of these complex media, and theories of inhomogeneous fluids that have potential applications to cellular environments. The workshop will serve as a catalyst for new breakthroughs in the study of macromolecular crowding.
We wish to ensure an intimate workshop setting, with no more than 20 to 25 participants. If you are interested in attending, but have not received an invitation, please contact the workshop organizer before registering.
Telluride Science is about expanding the frontiers of science, exploring new ideas, and building collaborations. The workshop schedule will allow for substantial unstructured time for participants to talk and think.
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Workshop Price: $ 299.00
Early Bird Lodging Discount Available Until: 02/01/2023
A $100.00 discount is applied to your lodging cost when you register before 02/01/2023.Cancellation Policy: Once a credit card has been charged, cancelled registrations will be subject to a cancellation fee. Registration fees will be automatically processed once registration is complete. A $25 cancellation fee will be retained from a registration refund. Lodging fee payments will be processed 60 days prior to arrival, and a $100 cancellation fee will apply if cancellations occur after a lodging fee payment is completed. Telluride Science can only guarantee a refund for the remaining lodging fees if requested prior to the cancellation deadline that is specific to each lodging provider. Telluride Science recommends that participants purchase travel insurance to protect against unforeseen, last-minute travel plan changes.
|DEY, DEBABRATA||Weizmann Institute of Science, Israel|
|Ebbinghaus, Simon||TU Braunschweig|
|Schuler, Benjamin||University of Zurich|