Workshop Details
Proton Transfer in Biology
08/02/2010 - 08/06/2010
Meeting Description:

Proton transfer reactions are of central importance in all areas of study concerning redox systems, ionic reactions and chemical catalysis, and there is significant recognition of the connection between biological and chemical reactions involving carbon acids and other very weakly acidic functionalities, i.e., the classical area of acid-base catalysis. However, the lack of detailed structural information has greatly impeded meaningful attention being paid to mechanisms of long-distance proton transport, in spite of its central role in bioenergy conversion by chemiosmotic systems. Recent successes in structure determination of the major energy-transducing membrane proteins have now set the stage for real advancement is this area. Just as the photosynthetic reaction center was invaluable for the development and testing of theoretical understanding of electron transfer in aperiodic systems, generally, so can proton transporting proteins can inform such developing fields as polymer membrane designs for fuel cells, non-aqueous electrolyte solutions, and matrix materials for heterogeneous catalysis. This is becoming an important focus area of productive cross-disciplinary exchange. The objective of the conference is to bring together scientists in diverse fields, who share interests in the structure and function of systems that transport protons and water. The emphasis is on long-range movements in biological membranes and model systems, but short-range proton and hydrogen atom transfers are also included to provide understanding of the nature of rate limiting events. The contributing fields include membrane biophysics, electrophysiology, structural biology of membrane proteins, bioenergetics, theoretical approaches to proton transfer, coupling of proton movements to electron transfer and conformational changes, molecular dynamics simulations, computation of protein electrostatics, spectroscopy and sensory transduction.

Meeting Venue:

Telluride Intermediate School
725 West Colorado Ave Telluride CO 81435

Proton Transfer in Biology Registered Meeting Participants:
Participant Organization
Agmon, Noam Hebrew University
Baptista, Antonio Instututo de Tecnologia Quimica e Biologica - UNL
Cui, Qiang Dept. of Chem. UW-Madison
Cukierman, Samuel Loyola Uiniversity Medical School/Physiology
DeCoursey, Thomas Rush University
Dencher, Norbert A. Technische Universitaet Darmstadt
Ferguson-Miller, Shelagh Michigan State University
Garcia-Moreno, Bertrand Johns Hopkins Univ.
Gennis, Robert University of Illinos
Gunner, Marilyn City College of New York
Gunner, Marilyn [2nd Reservation] City College of New York
Gutman, Menachem Tel Aviv University
Haines, Thomas H Rockefeller University
Hosler, Jonathan Univ. MS Medical Center
Machuqueiro, Miguel Faculty Sciences, University of Lisbon, Portugal
Moser, Christopher University of Pennsylvania
Nachliel, Esther Tel_Aviv University
Stuchebrukhov, Alexei UC Davis
Swanson, Jessica Dept. of Chemistry
Voth, Gregory Dept. of Chemistry
Voth, Gregory [5th Reservation] Dept. of Chemistry
Warshel, Arieh usc

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