Workshop Details
Proton Transfer in Biology
06/30/2014 - 07/04/2014
Meeting Description:

Proton transfer reactions are of central importance in all areas of study concerning redox systems, ionic reactions and chemical catalysis, and there is significant recognition of the connection between biological and chemical reactions involving carbon acids and other very weakly acidic functionalities, i.e., the classical area of acid-base catalysis. However, the lack of detailed structural information has greatly impeded meaningful attention being paid to mechanisms of long-distance proton transport, in spite of its central role in bioenergy conversion by chemiosmotic systems. Recent successes in structure determination of the major energy-transducing membrane proteins have now set the stage for real advancement is this area. Just as the photosynthetic reaction center was invaluable for the development and testing of theoretical understanding of electron transfer in aperiodic systems, generally, so can proton transporting proteins can inform such developing fields as polymer membrane designs for fuel cells, non-aqueous electrolyte solutions, and matrix materials for heterogeneous catalysis. This is becoming an important focus area of productive cross-disciplinary exchange. The objective of the conference is to bring together scientists in diverse fields, who share interests in the structure and function of systems that transport protons and water. The emphasis is on long-range movements in biological membranes and model systems, but short-range proton and hydrogen atom transfers are also included to provide understanding of the nature of rate limiting events. The contributing fields include membrane biophysics, electrophysiology, structural biology of membrane proteins, bioenergetics, theoretical approaches to proton transfer, coupling of proton movements to electron transfer and conformational changes, molecular dynamics simulations, computation of protein electrostatics, spectroscopy and sensory transduction.


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Supporting Files:

Meeting Venue:

Telluride Intermediate School
725 West Colorado Ave Telluride CO 81435

Proton Transfer in Biology Registered Meeting Participants:
Participant Organization
Adelroth, Pia Stockholm university
Arkin, Isaiah The Hebrew University
Brzezinski, Peter Stockholm University
Burnap, Robert Oklahoma State University
Cui, Qiang UW-Madison
DeCoursey, Thomas Rush University
Faraldo-Gomez, Jose National Institutes of Health
Ferguson-Miller, Shelagh Michigan State University
Gennis, Robert University of Illinois
Gunner, Marilyn City College of New York
Gutman, Menachem Tel Aviv University
Haines, Thomas RockefellerUniversity
Markland, Thomas Stanford University
Maupin, Christopher Colorado School of Mines
Meuwly, Markus University of Basel
Nachliel, Esther Tel Aviv University
Noskov, Sergei University of Calgary
Pomes, Regis Hospital for Sick Children
Shaw, Wendy Pacific Northwest National Laboratory

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